Platelet-Rich Plasma (PRP) therapy has become a cornerstone in regenerative medicine, aesthetic treatments, and sports medicine due to its ability to accelerate healing and tissue repair. One of the most critical factors in PRP’s effectiveness is platelet concentration—the higher the platelet count, the more growth factors are available for tissue regeneration.
But do PRP tubes affect platelet concentration? Absolutely! The type of PRP tube used directly influences the quality and quantity of platelets in the final PRP preparation. At IPPOCARE, we offer Classic PRP Tubes, a premium PRP tube with ACD and a specialized separating gel designed for high platelet recovery while ensuring convenience and safety. In this article, we’ll explain how PRP tubes impact platelet concentration and why our PRP tubes deliver optimal results.
What is Platelet-Rich Plasma (PRP) and What Is PRP Therapy?
What Is PRP?
Platelet-Rich Plasma (PRP) is a component of blood that contains a high concentration of platelets and growth factors, which play a crucial role in healing and tissue regeneration. PRP is derived from the patient’s own blood through a centrifugation process that separates red blood cells, white blood cells, and plasma, leaving behind a platelet-rich layer used for therapeutic applications.
What Is PRP Therapy Used For?
PRP therapy is widely used in various medical fields, including:
- Aesthetics & Anti-Aging – PRP is used for skin rejuvenation, hair restoration, and improving skin texture.
- Orthopedics & Sports Medicine – PRP injections help treat joint injuries, tendon damage, and osteoarthritis by stimulating tissue repair.
- Wound Healing – PRP accelerates healing in chronic wounds and surgical recovery.
- Dental & Oral Surgery – PRP supports faster healing of gum tissues and bone regeneration after extractions.
Since the effectiveness of PRP therapy depends on platelet concentration, the choice of PRP tube is critical.

How PRP Tubes Affect Platelet Concentration
PRP tubes play a crucial role in isolating and concentrating platelets from whole blood. Several factors impact platelet concentration and quality:
1. PRP Tubes with Gel: Do They Reduce Platelet Recovery?
A common concern is that PRP tubes with separating gel may trap platelets, reducing the final platelet concentration. However, not all gel-based tubes are the same—the composition and design of the gel determine its ability to retain platelets.
💡 IPPOCARE Classic PRP Tubes use an advanced gel separator that enhances platelet recovery while effectively removing unwanted red and white blood cells. Unlike lower-quality gel tubes that may trap platelets, our tubes are engineered for maximum platelet retention.
2. The Role of Anticoagulants in PRP Tubes
PRP tubes contain anticoagulants like ACD (Acid Citrate Dextrose), EDTA, or Heparin, which prevent blood clotting and maintain platelet integrity. However, different anticoagulants can impact platelet viability and activation:
- AACD (Acid Citrate Dextrose) is commonly used and preferred as it preserves platelets without prematurely activating them.
- Heparin may cause platelet clumping, reducing the final platelet concentration.
- EDTA is less commonly used for PRP preparation due to potential platelet damage.
✅ Our PRP tubes use ACD, ensuring platelet-rich plasma remains stable and potent for medical and aesthetic applications.
3. Tube Material and Centrifugation Efficiency
The design of PRP tubes, including material quality and compatibility with centrifuge settings, significantly affects platelet yield. Even with the same PRP tube, the centrifuge settings (RPM, G-force, and duration) significantly impact platelet concentration. A properly optimized protocol ensures that platelets are effectively separated and concentrated in the final plasma layer.
- Classic PRP Tubes are designed from medical-grade materials optimized for efficient platelet separation during centrifugation.
- Our tubes are designed to work with standard centrifuge protocols, ensuring consistent, high platelet concentration in every preparation.
Studies on PRP Tubes and Platelet Concentration
Several studies have investigated the impact of different anticoagulants and separating gels on platelet recovery in PRP preparation:
1. Anticoagulant Comparison
A study published in Bioengineering & Translational Medicine compared the effects of various anticoagulants on platelet-rich plasma. The researchers found that EDTA and heparin anticoagulation treatments significantly increased the platelet distribution width compared to ACD-A anticoagulation, indicating that ACD-A better preserves platelet integrity during PRP preparation.
2. Impact of Gel Separators
Research published in the Journal of Cutaneous and Aesthetic Surgery evaluated different PRP preparation methods and found that gel separator tubes did not increase platelet count but decreased it by 30%, accompanied by a lower growth factor release. This suggests that certain gel separators may trap platelets, reducing their availability in the final PRP product.
3. Anticoagulant Efficacy
A study in the Journal of Translational Medicine assessed the effects of different anticoagulants on platelet recovery. The findings indicated that ACD-A was superior to heparin and citrate in maintaining the integrity of platelet structures and preventing spontaneous activation during PRP preparation.
Why Choose IPPOCARE’s Classic PRP Tubes?
Choosing the right PRP tube is essential for maximizing platelet concentration and effectiveness. Here’s why Classic PRP Tubes stand out:
✅ Optimized Gel Separator – Specially formulated to retain platelets while filtering out unwanted blood components.
✅ ACD Anticoagulant – Ensures platelet integrity without early activation.
✅ Triple Sterilization – Guaranteed safe and contamination-free for professional use.
✅ High Platelet Recovery – Designed to concentrate platelets efficiently for enhanced PRP therapy results.
✅ Compatible with Most Centrifuges – No need for special equipment.
🔗 Discover Classic PRP Tubes for superior platelet-rich plasma preparation!

PRP tubes do affect platelet concentration, but not all gel-based tubes reduce platelet recovery. Classic PRP Tubes with ACD and an optimized separator gel are engineered to maximize platelet yield while maintaining ease of use, making them an ideal choice for professionals seeking consistent, high-quality PRP.
For the best PRP results, choosing the right PRP tube is just as important as using the correct centrifugation technique.
🔗 Upgrade your PRP therapy with Classic PRP Tubes, designed for high platelet concentration and professional-grade results.
FAQs
🔹 Does the gel in PRP tubes trap platelets?
Not all gel separators are the same! Classic PRP Tubes use a specialized gel that retains high platelet yield while effectively separating red blood cells.
🔹 Which anticoagulant is best for PRP?
ACD is the preferred anticoagulant because it preserves platelet integrity without premature activation. Our PRP tubes use ACD for maximum platelet viability.
🔹 How do Classic PRP Tubes compare to gel-free tubes?
While gel-free tubes require manual separation and have a higher risk of contamination, our PRP tubes with ACD and gel provide a convenient, efficient, and sterile solution for high platelet recovery.
🔹 Are Classic PRP Tubes compatible with my centrifuge?
Yes! Our tubes work with most standard centrifuges, ensuring easy integration into your PRP practice.
Maximize Your PRP Results with Classic PRP Tubes!
💉 Want a PRP tube that enhances platelet concentration while simplifying the process? Try Classic PRP Tubes today!
