Platelet-rich fibrin (PRF) therapy is an innovative regenerative treatment that harnesses the body’s natural healing properties to promote tissue repair and rejuvenation. Unlike traditional platelet-rich plasma (PRP), PRF is prepared without anticoagulants, allowing for a fibrin matrix that gradually releases growth factors over time. Our PRF tube is specifically designed to optimize this process, ensuring high-quality PRF for aesthetic, dental, orthopedic, and regenerative medical applications.lts.
Table of Contents (How to use PRF Tube?)
What is PRF?
Platelet-rich fibrin (PRF) is an advanced autologous blood concentrate used in regenerative medicine. It is derived from the patient’s own blood and processed without anticoagulants, allowing for a natural fibrin matrix to form. PRF contains a high concentration of platelets, leukocytes, and growth factors that promote accelerated healing and tissue regeneration. Unlike platelet-rich plasma (PRP), PRF provides a sustained release of growth factors over several days, making it highly effective for medical and aesthetic treatments, including wound healing, dental procedures, orthopedic therapy, and facial rejuvenation.

What is a PRF Tube?
A PRF tube is a specialized medical-grade container designed for the collection and processing of blood to create platelet-rich fibrin. These tubes are vacuum-sealed to ensure accurate blood collection and are free from anticoagulants to facilitate the natural formation of the fibrin matrix. PRF tubes are constructed from high-quality materials such as PET plastic or medical-grade glass and are optimized for low-speed centrifugation, which helps preserve the integrity of platelets and growth factors. Choosing the right PRF tube is essential for producing high-quality PRF for therapeutic use.

Features of Our PRF Tube
Our PRF tube is uniquely designed to facilitate the best possible PRF preparation. It does not contain anticoagulants, ensuring natural clot formation. Made from medical-grade PET plastic, it is optimized for low-speed centrifugation (1,300-2,700 rpm) to retain the maximum amount of platelets and leukocytes. The vacuum-sealed design ensures precise blood collection, while triple sterilization guarantees its safety for medical use. Our PRF tube is available exclusively in 10ml size, making it ideal for various regenerative applications.
Step-by-Step Guide: How to Use Our PRF Tube
Preparing the Patient
Before beginning the PRF preparation process, ensure the patient is well-hydrated. Reviewing their medical history and obtaining informed consent is essential. Additionally, the blood collection site must be disinfected to maintain sterility and prevent contamination.
Blood Collection Process
Using a sterile syringe and needle, blood is drawn from the patient and transferred directly into our vacuum-sealed 10ml PRF tube. Since PRF relies on natural clotting, no anticoagulants should be added.

Centrifugation Process
Once collected, the PRF tubes must be placed into a PRF-compatible centrifuge, ensuring they are evenly balanced to maintain stability. The centrifuge should be set at a speed of 1,300-2,700 rpm for 8-15 minutes, depending on the specific treatment protocol. The low-speed centrifugation process preserves the leukocytes and enables the formation of the fibrin clot necessary for PRF therapy.
PRF Separation and Collection
After centrifugation, the blood components will separate into three distinct layers. The red blood cells will settle at the bottom, while the PRF clot, rich in platelets, fibrin, and leukocytes, will form in the middle. The plasma will remain at the top. To extract the PRF clot, sterile forceps should be used carefully to preserve its structural integrity.
PRF Application
PRF can be applied in various ways depending on the treatment type. Injectable PRF is widely used in facial rejuvenation and hair restoration, while PRF membranes are beneficial for dental surgery, wound healing, and orthopedic procedures. Additionally, PRF can be combined with other regenerative treatments, such as HA fillers, stem cell therapy, and growth factor injections, to enhance its efficacy.
Post-Procedure Care
To ensure the best possible results, PRF should be applied immediately after extraction. Patients should be provided with aftercare instructions, including guidelines for proper wound care and activity limitations, to optimize healing and maximize regenerative benefits.
PRF Tube Centrifugation vs. PRP Centrifugation
There are distinct differences between PRF and PRP centrifugation protocols. PRF requires a lower centrifuge speed, typically between 1,300-2,700 rpm, and takes 8-15 minutes to process. PRP, on the other hand, is centrifuged at a higher speed of 3,000-5,000 rpm for 5-10 minutes. PRF does not use anticoagulants, allowing for the natural formation of a fibrin clot, whereas PRP requires anticoagulants to prevent clotting. PRF is best suited for long-term healing and regeneration, while PRP is used for the immediate release of platelets.
Choose the Right PRF Tube
Selecting the right PRF tube is essential for producing high-quality PRF. PRF tubes vary in sizes—10ml, 15ml, and 20ml—each designed to specific procedural needs. High-quality PRF tubes should be constructed from medical-grade glass or PET plastic and designed for low-speed centrifugation to maximize platelet and growth factor retention. It is vital to select tubes that are triple sterilized, vacuum-sealed, and compatible with PRF centrifuges to ensure consistent results. Here are some key factors to consider when choosing a PRF tube:
- Size and Volume: PRF tubes come in different sizes and volumes to accommodate different types of procedures and patients. Choose a tube that is appropriate for the specific procedure and volume of blood that will be collected.
- Material and Design: PRF tubes are made from different materials and designed with various features to enhance their performance and effectiveness. Look for a tube that is made from high-quality materials and has features that are designed to meet your specific needs.
- Centrifuge Compatibility: Different PRF tubes may be compatible with different types of centrifuges. Make sure to choose a tube that is compatible with the centrifuge you will be using to prepare the PRF.
- Manufacturer Reputation: Choose a PRF tube from a reputable manufacturer with a proven track record of producing high-quality and effective products.
- Cost: PRF tubes can vary in cost depending on the type, size, and features. While cost should not be the only factor in your decision, it is important to consider the cost of the tube when making your selection.
Blood Collection and Processing: Key to PRF Success
The effectiveness of PRF therapy begins with proper blood collection and processing. Before drawing blood, ensure the patient is well-hydrated and follow strict sterilization protocols. Using a sterile technique, the blood should be drawn into a PRF tube without delay to prevent premature clotting. PRF tubes must be centrifuged immediately at speeds between 1,300-2,700 rpm for 10-15 minutes, using a centrifuge that holds up to eight tubes with rounded bottoms. This process facilitates the separation of blood components into three layers: red blood cells at the bottom, PRF clot in the middle, and plasma at the top.
Key Steps for Collecting and Processing Blood for PRF Therapy
- Preparing the Patient: The patient should be properly prepared before the procedure. This includes reviewing their medical history, obtaining informed consent, and providing local anesthesia if needed.
- Blood Collection: The blood should be collected using a sterile technique and a properly designed blood collection tube. It is important to collect the appropriate volume of blood, as specified by the manufacturer of the PRF kit.
- Centrifugation: The blood is then placed in a centrifuge and spun at a specific speed and duration to separate the blood into its different components. The PRF will typically separate from the rest of the blood components and form a gel-like substance.
- PRF Collection: Once the PRF is separated, it should be carefully collected using sterile instruments and placed into a separate container. The PRF should be handled with care to avoid disrupting its structure and composition.
- PRF Application: The PRF can then be applied to the treatment area, typically by injection or topical application. The PRF should be used immediately after collection to ensure maximum effectiveness.
- Post-Procedure Care: After the procedure, the patient should be monitored for any adverse reactions or complications. They should also be provided with instructions for post-procedure care and follow-up appointments.
Use the PRF at the Right Time
Using PRF at the right time is crucial to its effectiveness in promoting healing and tissue regeneration. Here are some key factors to consider when determining the optimal timing for PRF treatment:
- Healing Timeline: Understanding the timeline for healing in the target tissue is essential. PRF is often most effective during the early stages of healing, when inflammation and cell proliferation are at their highest.
- Treatment Goals: The objective of the PRF treatment should guide its timing. If the goal is to reduce inflammation, PRF should be applied early in the healing process, whereas for tissue regeneration, it may be used later.
- Patient Factors: The patient’s overall health, medical conditions, and lifestyle can impact the timing of PRF therapy. These factors should be assessed to determine the most appropriate schedule.
- Treatment Schedule: Depending on the condition being treated, multiple PRF applications may be necessary over several weeks or months to achieve optimal results.
Ultimately, the best timing for PRF therapy depends on the specific patient and treatment objectives.
Consider Combination Therapy
PRF (Platelet-Rich Fibrin) can be used alone or in combination with other therapies to enhance its effectiveness. In fact, combining PRF with other therapies, such as stem cell therapy or growth factor injections, has been shown to produce even better results than using PRF alone.
For example, PRF can be used in conjunction with stem cell therapy to enhance the survival and growth of stem cells in the target tissue. This can help promote tissue regeneration and healing, particularly in cases where the tissue has been damaged or is slow to heal.
Similarly, combining PRF with growth factor injections can help stimulate the growth of new blood vessels and improve blood flow to the target tissue, which can help promote healing and regeneration.
It is important to note that the specific combination of therapies used will depend on the patient’s specific condition and treatment goals. Working with a healthcare professional who is experienced in PRF therapy and other regenerative medicine techniques can help ensure that the most appropriate treatment plan is developed to achieve the best possible outcomes.
PRF therapy is transforming regenerative medicine by offering a safe, natural, and highly effective approach to healing and rejuvenation. Proper selection, preparation, and application of PRF tubes are essential to achieving the best treatment outcomes. By using premium PRF tubes, adhering to precise centrifugation protocols, and integrating combination therapies, medical practitioners can enhance patient results significantly.
As PRF technology continues to evolve, it is becoming an indispensable tool across various medical disciplines. For professional guidance, PRF training, or bulk PRF tube orders, contact us today. Implementing best practices in PRF preparation and application ensures the maximum benefits of this groundbreaking regenerative therapy.
Our PRF tube is designed to deliver the highest quality PRF preparation. By eliminating anticoagulants, it preserves the natural fibrin matrix essential for tissue regeneration. It is specifically optimized for low-speed PRF centrifugation, ensuring greater platelet and leukocyte retention. With its sterile, vacuum-sealed design, our PRF tube meets the highest medical safety standards and is widely trusted by professionals in aesthetic, dental, orthopedic, and regenerative medicine.
If you are looking for a reliable and effective PRF solution, our 10ml PRF tube is the ideal choice. Order now to experience the full benefits of PRF therapy and elevate your regenerative treatments to the next level.